The Composition of the Chemicals, Antioxidants, and Anti-Microbial Agents on the Essential Oil of the Piper Species and Its Potential as A Natural Preservative: A Review

The production of safe food with a little to no artificial preservatives is the main and most important challenge for manufacturing industry. Increasing demand using has pushed industry use herbal or natural preservatives. essential oil piper species consists complex compounds like monoterpene that power in activity antioxidant antibacterial. object research Piper nigrum, betle, retrofractum, caninum, cubeba. review methodology used this PRISMA flowchart (2020). aims identify quality papers transparency number articles. objective summarize related chemical content oil, anti-microbe as potential on shows MIC score ranging from 1.5 12.8 mg/mL towards standard bacterial preventing pathogens foods. higher compared synthetic ones, BHA BHT have IC₅₀ <50 mg/mL. GRAS certification “safe” an additive Keywords: DPPH, Monoterpene, MIC, Sesquiterpene.